"The Magic School Bus" is an award-winning, animated children’s television series based on the book series of the same title by Joanna Cole and Bruce Degen. It is notable for its use of celebrity talent and being both highly entertaining and educational. Ralphie's upset when his mom tells him he's too sick to go to school because he was supposed to host a FNN (Frizzle News Network) TV broadcast on health that day. Not one to leave a student behind, Ms. Frizzle takes the class on a trip inside Ralphie's body to figure out what's ailing him. However, once inside, Ralphie's white blood cells see the bus as a threat and start to attack.