The 'Origin of Everything: The Origin of Gender' explores the historical and cultural development of gender concepts, challenging the binary notion of male and female. It delves into the distinction between gender and biological sex, highlighting the fluidity and diversity in gender identification across different societies. The video examines various global cultures where non-binary gender roles thrived, such as the Mahu in Hawaii and the Burrnesha in Albania. It discusses the Western historical context of gender, tracing how Enlightenment and colonial influences shaped today's binary gender perception. Viewers learn about the significance of gender roles in societal norms and labor division, referencing the research by Alberto Alesina and colleagues. The video emphasizes the ongoing conversations about gender in LGBTQIA rights and social discussions, providing a foundational understanding of gender's complex role in shaping human identity and society.