Science has made leaps and bounds in its assault on AIDS, but do antiretroviral drugs guarantee a long life? Why does the disease still cause widespread suffering in Africa, despite the development of new medicines? Author and actor Stephen Fry investigates, traveling across the United States, Great Britain, and Uganda as he studies the medical obstacles to an AIDS-free world. Fry highlights good news, such as reasonable longevity among many patients and the fact that healthy babies are born to infected mothers. He also laments the impact of late HIV diagnoses, the plight of patients who don't respond to medicine, and AIDS tragedies observed in and around Kampala, where corruption and drug supply problems typify Africa's vulnerability. NOTE: Contains occasional explicit language and imagery. Accessibility options on the DVD are: (1) expanded description, (2) English subtitles in a black box.